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Health and Fitness

Why IVF is Not 100% Successful in the First Cycle?

It is a fact that IVF is not 100% successful in the first cycle and that it is perfectly alright. Gynaecologists usually suggest a couple to have a complete 3 IVF cycles for higher chances of conceiving. But also, it does not mean that a couple cannot have a successful first IVF cycle.

Many couples do have a successful IVF in their very first attempt. There are several factors that affect and influence one’s ability to conceive through IVF. You can discuss the same with your gynaecologist as well. You can also consider Grace Fertility, the best fertility centre in Gurgaon for your further IVF cycles.

Moreover, this article briefs whether IVF is successful in the first cycle, why the first IVF cycle usually fails, and how you can increase your pregnancy chances in your further IVF cycles.

Is IVF successful in the first cycle?

There are several factors that affect and influence the result of an IVF cycle. As we talk about IVF being successful in the very first cycle, it depends on certain health factors.

Can IVF be successful in the first cycle? Absolutely. IVF is commonly recommended to couples who attempted natural pregnancy but failed. In clinical pregnancy, IVF helps couples with infertility to conceive.

Wonder how IVF works? When a couple is not able to conceive naturally due to infertility, IVF helps the woman get pregnant by removing her egg from ovaries, fertilizing it in a laboratory, and then returning it to her womb for further growth.

Now, if the IVF process goes right without any complications, your first IVF cycle will most likely be successful. On the other hand, if any complication occurs during or after the IVF cycle, it may affect the development of the embryo in the womb and cause your IVF cycle to fail.

Why does the first IVF cycle fail?

Since we are aware of the fact that some health complications can cause your first IVF cycle to fail, it is important that you are also aware of what these complications are. You can speak about it to a gynaecologist as well. Suggestively, you can consider GraceFertility, the best IVF centre in Gurgaon

Moreover, here is the list of reasons that commonly affect and influence the result of an IVF cycle:

  • Female Age: Age plays a key role in conceiving. As women grow older, it is common for them to have a decline in their egg quality and quantity. Now, if you wonder how that impacts the IVF cycle when a low-quality egg is taken for fertilization and then returned to the womb for growth, it might not develop and cause the IVF cycle to fail.
  • Ovarian Response: As the IVF treatment is started, the female partner is given a regular injection of follicle-stimulating hormone(FSH), a fertility hormone to increase egg production. In some women, more commonly in older women, this hormone might not respond correctly and fail to produce multiple eggs for collection.
  • Implantation failure: It means that the fertilized egg/embryo failed to implant in the womb. There are some reasons why it may happen such as infection of the uterus, presence of uterine polyps, premature increase in progesterone levels and very thin endometrial lining.
  • Genetic abnormality: It means that the embryo has missing, extra or irregular genetic DNA. In this situation, the body ultimately rejects the embryo which results in a failed IVF.
  • Lifestyle: Lifestyle might seem irrelevant to pregnancy, but it greatly affects and influences its chances. Couples who have maintained a healthy lifestyle months before, during, and after their IVF cycle have a comparatively higher chance of conceiving. On the other hand, a poor lifestyle can impact the IVF cycle otherwise.

Why do multiple IVF failures happen?

There may be any reason why your IVF cycle failed, and you must talk to your gynaecologist about it. Discuss with your gynaecologist what went wrong with your IVF and how you can fix them.

There are some common reasons why an IVF cycle fails, such as:

Female age

As women age, their egg quality and quantity begins to decline that causing difficulty in conceiving. Even with clinical pregnancy through IVF, the decline affects the chances of conceiving.

Low-quality eggs

Though it’s common for older women to have low-quality eggs, younger women can also have low-quality eggs. In clinical pregnancy through IVF, if a low-quality egg is fertilized, the embryo fails the implantation.

Sperm quality

Sperm quality significantly impacts IVF success rate. In clinical pregnancy through IVF, it is important that only the healthiest sperm is collected and used for fertilization. 

Low ovarian response

In IVF, a woman is given a regular injection of follicle-stimulating hormone (FSH), a fertility hormone that increases egg production. But, in some women, commonly older ones, this hormone does not respond properly and fails to produce multiple eggs for collection. 

Embryo implantation failure

There are several reasons why embryo implantation may fail, such as a premature spike in progesterone levels, an infection of the uterus, uterine polyps presence in the uterus. Well, embryo implantation failure is beyond one’s control but its cause can be identified through tests and be fixed.

Genetic abnormalities

Genetic or chromosomal abnormalities refers to the condition when chromosomal DNA has a missing, extra or irregular portion. In clinical pregnancy through IVF, such a case results in the body rejecting the embryo and causing the IVF cycle to eventually fail. 

Poor lifestyle

Lifestyle has a lot to do with fertility. Not just with a natural pregnancy, maintaining a good lifestyle and a healthy body weight months before your IVF cycle can improve its success rate. Studies have also found that women who follow an unhealthy lifestyle are more likely affected by infertility.

How to increase the chances of pregnancy with IVF?

You need to understand that it is absolutely fine if your first IVF cycle fails. One of the above-mentioned reasons might cause your IVF to fail, but, you can always take certain precautionary steps to increase your chances of conceiving in the next cycle.

First, you need to make sure that your gynaecologist is right for you. If not, you can always consider GraceFertility, the best IVF centre in Jammu for your further IVF treatment.

As we talk about the precautionary steps, these include some tests that your gynaecologist may suggest before starting with your IVF treatment. These tests will find out any complications that might affect the IVF and cause it to fail. These tests include uterine cavity assessment, sperm assessment, immune testing, infection screening and karyotyping.

Moreover, other than these tests or assessments, following a healthy lifestyle could also support the IVF, increasing the chances of conceiving. Consider exercising, having a nutritious diet, and avoiding smoking and alcohol.

Conclusion

In fact, your first IVF might not be successful, and it is absolutely alright. There might be some complications that cause the first cycle to fail, but, being aware of these complications and fixing them will eventually increase your chances of conceiving in the next IVF.

Gynaecologists usually suggest 3-IVF cycles for successful conceiving. So, if your first IVF cycle has failed, you still have two cycles left and with further tests and assessments, you will likely get pregnant. And you have to choose IVF centre smartly. 

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